"Best Friends Forever" is about Jessica (Jessica St. Clair)recieving divorce papers from her husband and her seeking comfort by flying to move in with her best friend Lennon (Lennon Parham). However, her boyfriend, Joe (Adam Pally), just moved into the apartment too and has turned Jessica's room into his own home office. When Jessica and Lennon do the girl things and connect more, Joe feels left out. Lennon wants to help and tries to balance both worlds. Jessica reconnects with Rav (Stephen Schneider) and tries to spark up the relationship again.